Jacqueline Sagen Selected Research

histogranin

1/2023	Attenuation of SCI-Induced Hypersensitivity by Intensive Locomotor Training and Recombinant GABAergic Cells.
1/2017	Experimental Gene Therapy with Serine-Histogranin and Endomorphin 1 for the Treatment of Chronic Neuropathic Pain.
1/2015	Viral vectors encoding endomorphins and serine histogranin attenuate neuropathic pain symptoms after spinal cord injury in rats.
4/2014	Selective antinociceptive effects of a combination of the N-methyl-D-aspartate receptor peptide antagonist [Ser(1)]histogranin and morphine in rat models of pain.
5/2007	Inhibition by the chromaffin cell-derived peptide serine-histogranin in the rat's dorsal horn.
1/2005	NMDA antagonist peptide supplementation enhances pain alleviation by adrenal medullary transplants.
1/2002	Selective antihyperalgesic effect of [Ser1] histogranin on complete Freund's adjuvant-induced hyperalgesia in rats.

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Jacqueline Sagen Research Topics

Disease

45	Pain (Aches) 03/2024 - 07/2000
21	Neuralgia (Stump Neuralgia) 01/2021 - 01/2002
19	Spinal Cord Injuries (Spinal Cord Injury) 01/2023 - 07/2003
14	Chronic Pain 01/2023 - 01/2002
11	Hyperalgesia 01/2021 - 01/2002
10	Hypersensitivity (Allergy) 01/2023 - 03/2007
9	Inflammation (Inflammations) 04/2024 - 01/2002
6	Peripheral Nerve Injuries 01/2022 - 03/2010
3	Peripheral Nervous System Diseases (PNS Diseases) 01/2020 - 03/2007
2	Cold Hypersensitivity 01/2023 - 05/2007
2	Spinal Cord Compression 12/2010 - 02/2009
2	Wounds and Injuries (Trauma) 08/2007 - 01/2007
1	Knee Osteoarthritis 03/2024
1	Pathologic Processes 01/2021
1	Neoplasms (Cancer) 01/2020
1	Hallucinations (Hallucination) 01/2017
1	HIV Infections (HIV Infection) 08/2015
1	Muscle Weakness 05/2013
1	Constipation 05/2013
1	Asthma (Bronchial Asthma) 02/2012
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2011

Drug/Important Bio-Agent (IBA)

18	Analgesics (Analgesic Drugs)IBA 01/2023 - 07/2000
10	Formaldehyde (Formol)FDA Link 01/2021 - 01/2005
9	Peptides (Polypeptides)IBA 01/2016 - 01/2002
7	histograninIBA 01/2023 - 01/2002
7	N-Methylaspartate (NMDA)IBA 01/2023 - 01/2002
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2017 - 01/2003
4	NeuropeptidesIBA 03/2024 - 01/2005
3	CytokinesIBA 01/2023 - 02/2012
3	Serine (L-Serine)FDA Link 01/2023 - 01/2015
3	ziconotide (Prialt)FDA Link 01/2022 - 02/2009
3	gamma-Aminobutyric Acid (GABA)IBA 01/2022 - 01/2012
3	Cannabinoid Receptor AgonistsIBA 01/2021 - 03/2007
3	CannabinoidsIBA 01/2021 - 03/2007
3	Glutamic Acid (Glutamate)FDA Link 01/2017 - 01/2011
3	LigandsIBA 04/2014 - 03/2007
3	Morphine (MS Contin)FDA LinkGeneric 04/2014 - 07/2000
3	Drug CombinationsIBA 05/2012 - 03/2010
3	(3R)- ((2,3- dihydro- 5- methyl- 3- ((4- morpholinyl)methyl)pyrrolo- (1,2,3- de)- 1,4- benzoxazin- 6- yl)(1- naphthalenyl))methanone (WIN 55,212)IBA 12/2011 - 03/2007
3	Glutamate Receptors (Glutamate Receptor)IBA 01/2011 - 01/2002
2	Transcription Factors (Transcription Factor)IBA 04/2024 - 08/2007
2	Substance PIBA 03/2024 - 03/2008
2	Calcitonin Gene-Related PeptideIBA 03/2024 - 04/2011
2	Conotoxins (Conotoxin)IBA 01/2022 - 02/2009
2	endomorphin 1IBA 01/2017 - 04/2014
2	Opioid Analgesics (Opioids)IBA 01/2017 - 07/2000
2	HIV Envelope Protein gp120IBA 01/2016 - 08/2015
2	EndocannabinoidsIBA 08/2015 - 01/2014
2	Gabapentin (Neurontin)FDA LinkGeneric 08/2015 - 12/2007
2	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 08/2015 - 01/2014
2	Opioid Peptides (Opioid Peptide)IBA 01/2015 - 04/2014
2	Ketamine FDA LinkGeneric 04/2014 - 05/2012
2	Quisqualic AcidIBA 01/2012 - 07/2008
2	Opiate AlkaloidsIBA 03/2010 - 06/2006
2	NF-kappa B (NF-kB)IBA 03/2010 - 05/2007
2	Tramadol (K315)FDA LinkGeneric 12/2007 - 03/2007
2	Freund's AdjuvantIBA 01/2003 - 01/2002
1	Phosphotransferases (Kinase)IBA 04/2024
1	p38 Mitogen-Activated Protein KinasesIBA 04/2024
1	MicroRNAs (MicroRNA)IBA 03/2024
1	caryophylleneIBA 01/2023
1	CannabidiolIBA 01/2023
1	Medical MarijuanaIBA 01/2023
1	Mollusk VenomsIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	N(1)-methyl-2-lysergic acid diethylamide (MIL)IBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2020
1	Mepivacaine (Carbocaine)FDA LinkGeneric 01/2016
1	Lidocaine (Xylocaine)FDA LinkGeneric 01/2016
1	Local AnestheticsIBA 01/2016
1	Oxidized CelluloseIBA 01/2016
1	cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester (URB597)IBA 08/2015
1	PF 3845IBA 08/2015
1	endomorphin 2IBA 04/2014
1	anandamide (arachidonylethanolamide)IBA 01/2014
1	AmidesIBA 01/2014
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2014
1	GABA-B ReceptorsIBA 05/2012
1	Butyrates (Butyrate)IBA 05/2012
1	GABA Agonists (GABA Receptor Agonists)IBA 05/2012
1	Aminobutyrates (Aminobutyric Acid)IBA 03/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2012
1	ibudilastIBA 02/2012
1	hemopressinIBA 09/2011
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 09/2011
1	GalaninIBA 04/2011
1	Riluzole FDA LinkGeneric 01/2011

Therapy/Procedure

11	Therapeutics 01/2021 - 07/2003
6	Transplantation 01/2020 - 07/2003
6	Drug Therapy (Chemotherapy) 01/2017 - 01/2002
4	Spinal Injections 01/2022 - 02/2009
3	Surgical Instruments (Clip) 01/2023 - 02/2012
3	Injections 01/2021 - 01/2005
2	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2023 - 01/2016
2	Ligation 02/2012 - 02/2009
2	Analgesia 01/2008 - 05/2007
1	Cell Transplantation 01/2022
1	Surgical Amputation (Amputations) 01/2021
1	Axotomy 01/2021
1	Combination Drug Therapy (Combination Chemotherapy) 01/2012